Imported pigs may have introduced the first classical swine influenza viruses into Mainland China
| Autor: | Lei Yang, Zi Li, Ming Li, Zai-Jiang Yu, Shumei Zou, Rongbao Gao, Xiaodan Li, Tian Bai, Shuai Yang, Min Wang, Dayan Wang, Libo Dong, Yuelong Shu, Wenfei Zhu, Yuan-ji Guo, Junfeng Guo |
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| Rok vydání: | 2013 |
| Předmět: |
Microbiology (medical)
Mainland China China Genes Viral Swine animal diseases viruses Chick Embryo Biology medicine.disease_cause Microbiology H5N1 genetic structure Virus Influenza A Virus H1N1 Subtype Orthomyxoviridae Infections Genetics medicine Influenza A virus Animals Humans Molecular Biology Phylogeny Ecology Evolution Behavior and Systematics Swine Diseases Phylogenetic tree Transmission (medicine) Classical swine H1N1 Genetic analysis virus diseases Antigenic analysis Sequence Analysis DNA Virology Swine influenza surveillance Influenza A virus subtype H5N1 Infectious Diseases Geographic origin |
| Zdroj: | Infection, Genetics and Evolution. 17:142-146 |
| ISSN: | 1567-1348 |
| Popis: | Objectives The first classical swine influenza A H1N1 viruses were isolated in Mainland China in 1991. To aid surveillance of swine influenza viruses as part of pandemic preparedness, we sought to identify their origin. Methods We sequenced and phylogenically analyzed 19 swine influenza viruses isolated in 1991 and 1992 in China and compared them with viruses isolated from other regions during the same period. Results All 19 swine influenza viruses analyzed in our study shared the highest similarity with the classical swine influenza virus A/Swine/Maryland/23239/1991 (H1N1). Phylogenetic trees of eight segmented genes exhibited similar topology, with all segments in the cluster of classical swine influenza viruses. In addition, antigenic analysis also indicated that the tested isolated were related to classical swine influenza isolates. Conclusions Classical swine H1N1 influenza viruses were predominant in Beijing pig herds during this period. Since both antibody and virus detections did not indicate the presence of CS H1N1 before 1991 in Mainland China, we combined with the data on pigs imported to and exported from China and concluded that these viruses might spread to China via pigs imported from North America and that they could affect the genetic evolution and transmission dynamics of swine influenza viruses in Hong Kong. |
| Databáze: | OpenAIRE |
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