Relation of renal thromboxane A2 production to urine flow, electrolyte excretion and plasma renin activity in control state and drug induced hypotension

Autor: K. Tihanyi, E. Mohacsi, B. Gachályi, I. Juhasz, B. Székács
Rok vydání: 1988
Předmět:
Zdroj: International Urology and Nephrology. 20:183-191
ISSN: 1573-2584
0301-1623
DOI: 10.1007/bf02550670
Popis: The functional importance of renal TxB2 generation in the maintenance of elevated arterial blood pressure in essential hypertension was followed in 22 patients, using the method of sustained blood pressure decrease by i.v. sodium nitroprusside infusion. Linear correlation between urinary excretion of TxB2, urine flow, and sodium excretion could be established in both control and hypotensive periods. Presumably, changes in urinary excretion of TxB2 reflect a secondary intrarenal counterregulatory response.
Databáze: OpenAIRE