Kinetic Resolution of Racemic Epoxides Using a Chiral Diamine Catalyst

Autor:	Pher G. Andersson, Arnaud Gayet
Rok vydání:	2005
Předmět:	Bicyclic molecule Chemistry Ligand Organic Chemistry Epoxide General Medicine Allylic alcohol Biochemistry Chiral resolution Kinetic resolution Chiral diamine Catalysis chemistry.chemical_compound Diamine Drug Discovery Organic chemistry
Zdroj:	ChemInform. 36
ISSN:	1522-2667 0931-7597
DOI:	10.1002/chin.200542118
Popis:	The kinetic resolution of a variety of racemic epoxides has been performed using a chiral bicyclic diamine ligand. Using 5 mol % of catalyst very high selectivity could be achieved; both epoxide and the corresponding allylic alcohol could be obtained in up to 99% ee.
Databáze:	OpenAIRE
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