Cross-neutralization tests among Cache Valley virus isolates revealing the existence of multiple subtypes
| Autor: | Thomas P. Monath, Charles H. Calisher, Wolff Kl, Marta S. Sabattini |
|---|---|
| Rok vydání: | 1988 |
| Předmět: |
Virus quantification
biology Cache-Valley virus viruses Bunyaviridae Viral Plaque Assay Cross Reactions medicine.disease medicine.disease_cause biology.organism_classification Arbovirus Virology Virus Infectious Diseases Maguari virus Bunyamwera virus Neutralization Tests medicine Antigenic variation Parasitology Antigens Viral |
| Zdroj: | The American journal of tropical medicine and hygiene. 39(2) |
| ISSN: | 0002-9637 |
| Popis: | Maguari virus has been classified as a subtype of Cache Valley virus. Seven Bunyamwera serogroup viruses (including prototypes Cache Valley and Maguari viruses), 4 viruses shown in previous tests as close antigenic relatives of Maguari or Cache Valley viruses, and Xingu virus were cross-tested by serum dilution-plaque reduction neutralization. All viruses were distinguishable from prototypes Cache Valley and Maguari viruses. The close antigenic relationships of the Cache Valley-like viruses demonstrate that multiple subtypes of Cache Valley virus exist and suggest that such antigenic variation is a phenotypic expression of considerable genetic diversity. |
| Databáze: | OpenAIRE |
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