TESTICULAR SUBSTANCE IMPLANTATION

Autor: L. L. Stanley
Rok vydání: 1921
Předmět:
Zdroj: Endocrinology. 5:708-714
ISSN: 1945-7170
0013-7227
DOI: 10.1210/endo-5-6-708
Popis: Brown-Sequard (1) in 1889 made a number of experiments with an extract produced from the testicles of various animals. He became so convinced of the beneficial effects of this material when injected into older animals, that he determined to experiment with it upon himself. On May 15, with the assistance of his co-workers, he excised one of the testicles from a vigorous dog two years of age, cut it into pieces, ground it in a mortar with a small amount of water, and expressed the fluid. By filtration abtmt 4½ c.c. of extract was obtained. He injected 1 c.c. of this extract subcutaneously into his own leg, repeating the injection about every five to ten days, until he had received ten treatments in all. The last five were made from the extract of guinea pig testicles, which was injected under the skin of the abdomen and arm.
Databáze: OpenAIRE