Italian Survey on Comparative Levofloxacin Susceptibility in 334 Clinical Isolates of Pseudomonas aeruginosa
| Autor: | Bernardetta Segatore, Nicola Franceschini, Domenico Setacci, Federico Marchetti, Mariagrazia Perilli, Annalisa De Santis, Gianfranco Amicosante |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
Ofloxacin
Imipenem Ceftazidime Levofloxacin Microbial Sensitivity Tests Microbiology Anti-Infective Agents Intensive care polycyclic compounds medicine Humans heterocyclic compounds Pharmacology (medical) Antibacterial agent Pharmacology business.industry Drug Resistance Microbial biochemical phenomena metabolism and nutrition bacterial infections and mycoses Drug Resistance Multiple Cephalosporins Ciprofloxacin Intensive Care Units Infectious Diseases Italy Susceptibility Amikacin Pseudomonas aeruginosa business medicine.drug |
| Zdroj: | Scopus-Elsevier |
| ISSN: | 1098-6596 0066-4804 |
| DOI: | 10.1128/aac.43.2.428 |
| Popis: | A national survey on susceptibility patterns of 334 Pseudomonas aeruginosa isolates from intensive care units and hematology and oncology wards from 13 Italian hospitals compared the in vitro activity of levofloxacin, an injectable oral fluoroquinolone, to those of ciprofloxacin, ofloxacin, ceftazidime, imipenem, amikacin, and gentamicin. Amikacin and imipenem had the best susceptibility profiles. The activity of levofloxacin was superior to those of the other quinolones and was comparable to that of ceftazidime. The effect of levofloxacin in vitro on P. aeruginosa clinical isolates suggests that further clinical investigations are warranted. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|