The chemical composition and anti-inflammatory effect of the essential oil obtained from Abeliophyllum distichum flowers
| Autor: | Heung Bin Lim, Tae Kyung Hyun, Hyun Ju Ju |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
biology
medicine.drug_class Plant Science biology.organism_classification abeliophyllum distichum Abeliophyllum Anti-inflammatory anti-inflammation essential oil law.invention Proinflammatory cytokine pro-inflammatory mediator chemistry.chemical_compound Forsythia chemistry Linalool law medicine Food science QK900-989 Plant ecology Chemical composition Methyl salicylate Essential oil |
| Zdroj: | Botanica Serbica, Vol 45, Iss 1, Pp 137-142 (2021) |
| ISSN: | 1821-2638 1821-2158 |
| Popis: | In the present study, the chemical composition of the essential oil (EO) obtained from the flowers of Abeliophyllum distichum, commonly known as white forsythia, was examined by gas chromatography-mass spectrometry (GC/MS). Thirty-five components including epoxy linalool, methyl salicylate, linalool oxide (pyranoid), and L-linalool were identified in the EO of A. distichum flowers (AfEO). In addition, the AfEO exhibited a remarkable anti-inflammatory effect in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells. We found that this anti-inflammatory effect was mediated by inhibiting the expression of proinflammatory mediators, including IL-1?, IL-6, and IL-18. Taken together, these results confirm the potential use of the AfEO as an anti-inflammatory agent for topical application. |
| Databáze: | OpenAIRE |
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