Possible Neoangiogenesis in Achilles Tendon Xanthoma with Familial Hypercholesterolemia: A Novel Approach to Achilles Tendon Xanthoma
| Autor: | Kai Ninomiya, Masahiko Asami, Hitomi Yuzawa, Jiro Aoki, Kota Komiyama, Osamu Wada, Kazuyuki Yahagi, Akitake Suzuki, Tetsu Tanaka, Yu Horiuchi, Kazuho Ishizaki, Jun Tanaka, Kengo Tanabe |
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| Rok vydání: | 2021 |
| Předmět: |
neoangiogenesis
Pathology medicine.medical_specialty Case Report Familial hypercholesterolemia 030204 cardiovascular system & hematology Xanthoma Achilles Tendon achilles tendon xanthoma Imaging modalities Hyperlipoproteinemia Type II 03 medical and health sciences 0302 clinical medicine Xanthomatosis Internal Medicine medicine magnetic resonance imaging Humans Doppler Ultrasound Imaging superb micro-vascular imaging Achilles tendon familial hypercholesterolemia medicine.diagnostic_test business.industry X-Rays Cholesterol crystals Magnetic resonance imaging ultrasonography General Medicine medicine.disease medicine.anatomical_structure 030211 gastroenterology & hepatology business Microvascular flow |
| Zdroj: | Internal Medicine |
| ISSN: | 1349-7235 0918-2918 |
| DOI: | 10.2169/internalmedicine.7326-21 |
| Popis: | Achilles tendon xanthoma (ATX) is one of the typical features of familial hypercholesterolemia (FH). The morphological evaluation of ATX by X-ray radiography is widely recognized; however, the utility of other imaging modalities remains unclear. We herein report two cases of FH in which Doppler ultrasound imaging demonstrated a microvascular flow in ATX that only rarely could be observed in normal Achilles tendons. Neoangiogenesis accompanies chronic inflammation and it may play an important role in the deposition of cholesterol crystals leading to ATX. In addition to the morphological evaluation of ATX, the assessment of neoangiogenesis may therefore be essential for the evaluation of ATX. |
| Databáze: | OpenAIRE |
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