Evaluation of REMEDi HS in the Diagnosis of Dimethoate Poisoning
Autor: | Ralf Regenthal, Heiner Trauer, Mario Krueger, Rainer Preiss, Reinhard Boehm |
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Rok vydání: | 2002 |
Předmět: |
Adult
Male Drug Insecticides media_common.quotation_subject Drug profiling Clinical toxicology Gas Chromatography-Mass Spectrometry chemistry.chemical_compound medicine Humans Dimethoate Pharmacology (medical) Chromatography High Pressure Liquid media_common Pharmacology Chromatography medicine.diagnostic_test Poisoning Serum concentration Serum samples Quantitative determination Suicide chemistry Therapeutic drug monitoring Drug Monitoring |
Zdroj: | Therapeutic Drug Monitoring. 24:297-301 |
ISSN: | 0163-4356 |
DOI: | 10.1097/00007691-200204000-00011 |
Popis: | The authors describe the evaluation of an automated rapid emergency drug profiling system (REMEDi HS), which is designed for clinical toxicology and therapeutic drug monitoring, in a severe case of dimethoate poisoning. Successful qualitative and quantitative determination of dimethoate in diluted serum samples was achieved. The authors found that dimethoate serum concentrations were properly measured with the REMEDi method and well correlated with gas chromatography-mass spectrometry. The results provide evidence that besides screening and rapid estimation of drug concentrations in human fluids, this system is a suitable tool in cases of symptomatic dimethoate poisoning. |
Databáze: | OpenAIRE |
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