Factors influencing nerve regeneration in a trial of timcodar dimesylate
| Autor: | B. G. Petty, Justin C. McArthur, Peter Hauer, Michael Sirdofsky, B. Murinson, Michael Polydefkis |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Adult
Male Pain Threshold medicine.medical_specialty Pyridines Biopsy Placebo-controlled study Nerve fiber Biology Placebo Double blind Nerve Fibers Double-Blind Method Peripheral Nerve Injuries medicine Humans Peripheral Nerves Regeneration (biology) Nerve injury Middle Aged Timcodar Dimesylate Surgery Nerve Regeneration medicine.anatomical_structure Thigh Touch Anesthesia Sensory Thresholds Wounds and Injuries Neurophilin Female Neurology (clinical) medicine.symptom Epidermis |
| Zdroj: | Neurology. 66(2) |
| ISSN: | 1526-632X |
| Popis: | The authors assessed the ability of the neurophilin compound, timcodar dimesylate, to accelerate the return of epidermal nerve fiber density (ENFD) after a standardized nerve injury in a randomized double blind, placebo controlled trial. While there was no difference in the regeneration rate between the treatment and placebo arms, the baseline ENFD (p = 0.006), height (p = 0.02), and race (p = 0.03) were associated with the regeneration rate. |
| Databáze: | OpenAIRE |
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