Synthesis and photochemical behavior of coumarin-caged cholesterol
| Autor: | Cynthia V. Stauffacher, Paul Helquist, Guillermo Ferraudi, Qian Peng, Olaf Wiest, Pauline Bourbon |
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| Rok vydání: | 2013 |
| Předmět: |
Molecular Structure
Chemistry Organic Chemistry Clinical Biochemistry Photodissociation Pharmaceutical Science Quantum yield Photochemical Processes Photochemistry Coumarin Biochemistry chemistry.chemical_compound Cholesterol Coumarins Drug Discovery Quantum Theory Molecular Medicine Organic chemistry Molecular Biology Derivative (chemistry) |
| Zdroj: | Bioorganic & Medicinal Chemistry Letters. 23:2162-2165 |
| ISSN: | 0960-894X |
| DOI: | 10.1016/j.bmcl.2013.01.095 |
| Popis: | The syntheses of three coumarin-caged cholesterols are reported that contain the 6-diethylaminocoumarin (DEACM), 6-bromo-7-hydroxycoumarin (BHC) and 6-bromo-7-methoxycoumarin (BMCM) photocleavable groups. Upon photolysis, the best caged derivative was found to be BHC-cholesterol whose quantum yield was determined to be 0.032 at 350 nm. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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