Brush Swelling and Attachment Strength of Barnacle Adhesion Protein on Zwitterionic Polymer Films as a Function of Macromolecular Structure
| Autor: | E. Stefan Kooij, Robert Quintana, Vivek Arjunan Vasantha, Shifeng Guo, G. Julius Vancso, Marco Cirelli, Dominik Jańczewski, Zi S. D. Toa |
|---|---|
| Přispěvatelé: | Materials Science and Technology of Polymers, Physics of Interfaces and Nanomaterials |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
chemistry.chemical_classification
Atom-transfer radical-polymerization Chemistry Solvation Force spectroscopy Ionic bonding 02 engineering and technology Surfaces and Interfaces Adhesion Polymer 010402 general chemistry 021001 nanoscience & nanotechnology Condensed Matter Physics 01 natural sciences 0104 chemical sciences chemistry.chemical_compound Monomer Chemical engineering Electrochemistry medicine General Materials Science Swelling medicine.symptom 0210 nano-technology Spectroscopy |
| Zdroj: | Langmuir, 35(24), 8085-8094. American Chemical Society |
| ISSN: | 0743-7463 |
| Popis: | [Image: see text] The exceptional hydration of sulfobetaine polymer brushes and their resistance toward nonspecific protein absorption allows for the construction of thin films with excellent antibiofouling properties. In this work, swollen sulfobetaine brushes, prepared by surface-initiated atom transfer radical polymerization of two monomers, differentiated by the nature of the polymerizable group, are studied and compared by a liquid-cell atomic force microscopy technique and spectroscopic ellipsometry. Colloidal AFM-based force spectroscopy is employed to estimate brush grafting density and characterize nanomechanical properties in salt water. When the ionic strength-induced swelling behaviors of the two systems are compared, the differences observed on the antipolyelectrolyte response can be correlated with the stiffness variation on brush compression, likely to be promoted by solvation differences. The higher solvation of amide groups is proposed to be responsible for the lower adhesion force of the barnacle cyprid’s temporary adhesive proteins. The adhesion results provide further insights into the antibiofouling activity against barnacle cyprid settlement attributed to polysulfobetaine brushes. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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