Comparative Effectiveness of the Homeopathic Preparation Traumeel S in Third Molar Extraction Surgery: A Preliminary Triple-Blind Clinical Trial
| Autor: | Saulo Gabriel Moreira Falci, Marcos Luciano Pimenta Pinheiro, Ighor Andrade Fernandes, Glaciele Maria de Souza |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Molar
Adult Male medicine.medical_specialty Visual analogue scale Anti-Inflammatory Agents Trismus Asymptomatic Dexamethasone 03 medical and health sciences Young Adult 0302 clinical medicine Double-Blind Method Edema Statistical significance medicine Humans Prospective Studies Minerals Pain Postoperative business.industry Plant Extracts Tooth Impacted 030206 dentistry Homeopathy Surgery Complementary and alternative medicine 030220 oncology & carcinogenesis Traumeel S Female Molar Third medicine.symptom business medicine.drug |
| Zdroj: | Homeopathy : the journal of the Faculty of Homeopathy. 110(4) |
| ISSN: | 1476-4245 |
| Popis: | Background and Aim This preliminary study aimed to evaluate whether a homeopathic preparation (Traumeel S) might be a good option to control post-operative outcomes (pain, edema and trismus) associated with surgical removal of mandibular third molar teeth. The null hypothesis was that Traumeel S is not different from dexamethasone (gold standard) in controlling these post-operative inflammatory complications. Methods A randomized, “split-mouth”, triple-blind clinical trial was conducted. Seventeen healthy patients with a mean age of 20.94 ( ± 5.83) years had their lower asymptomatic bilateral third molars removed. Patients were randomized to receive Traumeel S or dexamethasone pre-operatively by injection into the masseter muscle; each patient acted as his/her own control. At 24, 48, 72 hours and 7 days after the surgery, the pain was evaluated according to a visual analog scale, edema through linear measurements of the face, and trismus through the maximum buccal opening. Wilcoxon statistics or paired t-test were used, and a significance level of 95% was adopted. Results For pain, the results for Traumeel S were not different (p > 0.05) from those of dexamethasone after 24 hours, 72 hours, and 7 days. For edema, the results for Traumeel S were not different (p > 0.05) from those of dexamethasone at all post-operative evaluations. For mouth opening, the results for Traumeel S were not different (p > 0.05) from those of dexamethasone at 72 hours and 7 days after third molar extraction. Conclusion With the exception of some early post-operative findings, the null hypothesis is not rejected. Traumeel S might be a good alternative approach to dexamethasone for controlling pain, edema and trismus after third molar removal. |
| Databáze: | OpenAIRE |
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