Klinefelter's Syndrome and Breast Cancer
| Autor: | H Würz, R Mies, B Pfeiff, W Winkelmann, H Fischer |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Adult
Male Oncology medicine.medical_specialty Urology Estrogen receptor Breast Neoplasms Klinefelter Syndrome Endocrinology Breast cancer Internal medicine Humans Medicine Testosterone Receptor S syndrome Estradiol business.industry General Medicine medicine.disease Tumor tissue Receptors Estrogen Etiology business Estradiol serum |
| Zdroj: | Andrologia. 14:317-321 |
| ISSN: | 1439-0272 0303-4569 |
| Popis: | Breast cancer in a patient with Klinefelter's syndrome is reported. Possible correlation between testosterone and estradiol serum levels after testosterone-enanthate substitution, estrogen receptors in tumor tissue and clinical symptomatology are discussed. The various theories of etiology concerning breast cancer in this syndrome are reviewed. The increased conversion of testosterone to estradiol at the therapy with androgens might be responsible for the development of breast cancer in Klinefelter's syndrome. The current way of treatment is described. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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