Prothrombotic hemostasis disturbances in patients with severe COVID-19: Individual daily data

Autor: Sarah Lessire, Hugues Jacqmin, Isabelle Michaux, Sophie Testa, Geoffrey Horlait, Marion Bareille, Jonathan Douxfils, Silvy Laporte, Céline Chapelle, A. Dive, François Mullier, Thomas Lecompte, Jean-Michel Dogné, Michael Hardy, Pierre Bulpa
Přispěvatelé: UCL - SSS/IREC/MEDA - Pôle de médecine aiguë, UCL - (MGD) Services des soins intensifs, UCL - SSS/IREC/MONT - Pôle Mont Godinne, UCL - (MGD) Laboratoire de biologie clinique, UCL - (MGD) Service d'anesthésiologie
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Data in Brief, Vol 33, Iss, Pp 106519-(2020)
Data in Brief
Hardy, M, Michaux, I, Lessire, S, Douxfils, J, Dogné, J-M, Bareille, M, Horlait, G, Bulpa, P, Chapelle, C, Laporte, S, Testa, S, Jacqmin, H, Lecompte, T, Dive, A & Mullier, F 2020, ' Prothrombotic Hemostasis Disturbances in Patients with Severe COVID-19 : Individual daily data ', Data in Brief, vol. 33, 106519, pp. 106519 . https://doi.org/10.1016/j.dib.2020.106519
Data in brief, Vol. 33, p. 106519 (2020)
ISSN: 2352-3409
Popis: This data article accompanies the manuscript entitled: “Prothrombotic Disturbances of hemostasis of Patients with Severe COVID-19: a Prospective Longitudinal Observational Cohort Study” submitted to Thrombosis Research by the same authors. We report temporal changes of plasma levels of an extended set of laboratory parameters during the ICU stay of the 21 COVID-19 patients included in the monocentre cohort: CRP, platelet count, prothrombin time; Clauss fibrinogen and clotting factors II, V and VIII levels, D-dimers, antithrombin activity, protein C, free protein S, total and free tissue factor pathway inhibitor, PAI-1 levels, von Willebrand factor antigen and activity, ADAMTS-13 (plasma levels); and of two integrative tests of coagulation (thrombin generation with ST Genesia) and fibrinolysis (global fibrinolytic capacity - GFC). Regarding hemostasis, we used double-centrifuged frozen citrated plasma prospectively collected after daily performance of usual coagulation tests. Demographic and clinical characteristics of patients and thrombotic and hemorrhagic complications were also collected from patient's electronic medical reports.
Databáze: OpenAIRE