Immunohistochemical Detection of Porcine Reproductive and Respiratory Syndrome Virus Antigen in Neurovascular Lesions
| Autor: | Patrick G. Halbur, John J. Andrews, Roongroje Thanawongnuwech |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
0301 basic medicine
Pathology medicine.medical_specialty Myocarditis Swine 040301 veterinary sciences Central nervous system Porcine Reproductive and Respiratory Syndrome Viremia Weaning Biology 0403 veterinary science 03 medical and health sciences medicine Animals Porcine respiratory and reproductive syndrome virus Antigens Viral Paresis General Veterinary Brain 04 agricultural and veterinary sciences medicine.disease Porcine reproductive and respiratory syndrome virus biology.organism_classification Immunohistochemistry Animals Suckling 030104 developmental biology medicine.anatomical_structure Gliosis Immunology Female medicine.symptom Vasculitis Encephalitis |
| Zdroj: | Journal of Veterinary Diagnostic Investigation. 9:334-337 |
| ISSN: | 1943-4936 1040-6387 |
| DOI: | 10.1177/104063879700900323 |
| Popis: | At necropsy, no gross lesions were observed except for reddish consolidation of approximately 10% of the anterioventral portions of the lungs in 1 pig. Likewise, no significant gross lesions were seen in the tissues submitted from the sow. Results of experimental studies indicate that PRRSV infection is a multisystemic disease characterized initially by viremia with subsequent virus distribution and replication in multiple organs, causing interstitial pneumonia, lymphadenopathy, myocarditis, and encephalitis. 5-8,16,18 Nervous signs are uncommonly reported and are described as incoordination, paresis, splay-leggedness, and tremors in young pigs. Characteristic PRRSV-induced central nervous system (CNS) lesions include encephalitis with lymphohistiocytic perivascular cuffing, gliosis, and less often mild vasculitis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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