Visual short-term memory binding deficit with age-related hearing loss in cognitively normal older adults
| Autor: | Brian A. Lawlor, Mario A. Parra, David G. Loughrey |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Male
0301 basic medicine medicine.medical_specialty Hearing loss lcsh:Medicine BF Disease Audiology Predictive markers Article 03 medical and health sciences Cognition 0302 clinical medicine medicine Humans Dementia Visual short-term memory Risk factor Cognitive decline lcsh:Science Aged Multidisciplinary Cognitive ageing business.industry lcsh:R Presbycusis medicine.disease Memory Short-Term 030104 developmental biology Visual Perception Female lcsh:Q medicine.symptom business Neurocognitive 030217 neurology & neurosurgery |
| Zdroj: | Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019) Scientific Reports |
| ISSN: | 2045-2322 |
| DOI: | 10.1038/s41598-019-49023-1 |
| Popis: | Age-related hearing loss (ARHL) has been posited as a possible modifiable risk factor for neurocognitive impairment and dementia. Measures sensitive to early neurocognitive changes associated with ARHL would help to elucidate the mechanisms underpinning this relationship. We hypothesized that ARHL might be associated with decline in visual short-term memory binding (VSTMB), a potential biomarker for preclinical dementia due to Alzheimer’s disease (AD). We examined differences in accuracy between older adults with hearing loss and a control group on the VSTMB task from a single feature (shapes) condition to a feature binding (shapes-colors) condition. Hearing loss was associated with a weaker capacity to process bound features which appeared to be accounted for by a weaker sensitivity for change detection (A’). Our findings give insight into the neural mechanisms underpinning neurocognitive decline with ARHL and its temporal sequence. |
| Databáze: | OpenAIRE |
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