Classic biphasic pulmonary blastoma (CBPB): a rare primary pulmonary malignancy
| Autor: | Angela McKinnie, William Wallace, Malcolm Will, Shashank Pooniya, Thomas Taylor |
|---|---|
| Rok vydání: | 2023 |
| Předmět: |
medicine.medical_specialty
Lung Lung Neoplasms medicine.diagnostic_test business.industry medicine.medical_treatment Biphasic Pulmonary Blastoma General Medicine Malignancy medicine.disease Prognosis Radiation therapy medicine.anatomical_structure Cardiothoracic surgery Biopsy medicine Humans Female Radiology Chest radiograph business Tomography X-Ray Computed Survival rate Pulmonary Blastoma |
| Zdroj: | BMJ case reports. 14(8) |
| ISSN: | 1757-790X |
| Popis: | Classic biphasic pulmonary blastoma (CBPB) is a very rare primary pulmonary malignancy with distinctive clinical and pathological features. Usually CBPB presents with either non specific symptoms or is diagnosed incidentally. Histologically CBPB is composed of a mixture of malignant epithelial and stromal cells resembling fetal lung tissue. Surgical resection is the mainstay of treatment with further chemotherapy or radiotherapy on a case-by-case basis. However, due to its rarity, no definite treatment guidelines are available. CBPB overall has a very poor prognosis with a 5-year survival rate of only 15%. Our patient presented with cough and haemoptysis. Her chest radiograph demonstrated a large right-sided lung mass. Further investigations included CT, CT-guided biopsy and PET CT which were discussed at multidisciplinary team meetings. The patient then underwent complete surgical excision. We report this rare malignancy with radiological and pathological features, comparing them with previously reported cases. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|