Microstructure arrays of DNA using topographic control
| Autor: | Hyoungsoo Kim, Yun Jeong Cha, Dong Ki Yoon, Soon Mo Park, Ra You |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Materials science Science General Physics and Astronomy Biocompatible Materials Nanotechnology 02 engineering and technology Supramolecular polymers Article General Biochemistry Genetics and Molecular Biology 03 medical and health sciences chemistry.chemical_compound Microscopy Microtechnology lcsh:Science Oligonucleotide Array Sequence Analysis Shearing (physics) Microscopy Confocal Multidisciplinary Liquid crystalline Biomaterial DNA General Chemistry 021001 nanoscience & nanotechnology Microstructure 030104 developmental biology chemistry DNA and RNA lcsh:Q Stress Mechanical 0210 nano-technology Patterned substrate |
| Zdroj: | Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019) Nature Communications |
| ISSN: | 2041-1723 |
| Popis: | DNA is a common biomaterial in nature as well as a good building block for producing useful structures, due to its fine feature size and liquid crystalline phase. Here, we demonstrate that a combination of shear-induced flow and microposts can be used to create various kinds of interesting microstructure DNA arrays. Our facile method provides a platform for forming multi-scale hierarchical orientations of soft- and biomaterials, using a process of simple shearing and controlled evaporation on a patterned substrate. This approach enables potential patterning applications using DNA or other anisotropic biomaterials based on their unique structural characteristics. DNA is a biological building block which has drawn much attention as a structural material for a range of applications. Here, the authors report that DNA structures can be templated using shear-induced flow and microposts for controllable DNA patterning. |
| Databáze: | OpenAIRE |
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