The association between body mass index and immunohistochemical subtypes in breast cancer
| Autor: | Gökmen Umut Erdem, Ali R Sever, Yavuz Ozisik, Fatih Karatas, Aydin Aytekin, Kadri Altundag, Suleyman Sahin |
|---|---|
| Přispěvatelé: | Temel Onkoloji |
| Rok vydání: | 2017 |
| Předmět: |
Adult
0301 basic medicine medicine.medical_specialty Adolescent Receptor ErbB-2 R/W - Tıp Breast Neoplasms Immunohistochemical subtypes Overweight Gastroenterology Body Mass Index Young Adult 03 medical and health sciences Breast cancer 0302 clinical medicine Internal medicine Humans Medicine Obesity Young adult Survival analysis Aged Retrospective Studies Premenopausal Aged 80 and over Gynecology business.industry Incidence (epidemiology) Retrospective cohort study General Medicine Middle Aged medicine.disease Immunohistochemistry Survival Analysis Postmenopause 030104 developmental biology Premenopause 030220 oncology & carcinogenesis Postmenopausal Female Surgery medicine.symptom business Body mass index |
| Zdroj: | The Breast. 32:227-236 |
| ISSN: | 0960-9776 |
| Popis: | Background:Body mass index (BMI) is defined as a poor prognostic factor in patients with breast cancer(BC). However, there are controversial results regarding the various effects of BMI on BC, hence the exactpathophysiology of the relation between obesity and BC is still under debate, and remains unclear. Thispaper aims to investigate the association between BMI at presentation and BC subtypes defined accordingto the immunohistochemical classification in both premenopausal and postmenopausal patients with BC.Patients and methods:This study is a retrospective and explorative analysis of the 3767 female BC pa-tients from a single center. All patients' BMI at the time of initial diagnosis and tumor demographics wererecorded. BMI was stratified into 3 groups as normal-weighted (BMI |
| Databáze: | OpenAIRE |
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