Speckle tracking echocardiography can predict subclinical myocardial involvement in patients with sarcoidosis: A meta‐analysis

Autor:	Adnan Kharsa, Mohan Rao, Devesh Rai, Mohamed Abdelazeem, Myriam Amsallem, Ahmed M Altibi, Vishal Parikh, Kirolos Barssoum, Scott Feitell, Medhat Chowdhury, Navin C. Nanda, Mallory Balmer-Swain, Ahmed Abuzaid, Ashish Kumar, Sara Shahid, Bipul Baibhav, Samarthkumar Thakkar
Rok vydání:	2020
Předmět:	medicine.medical_specialty Sarcoidosis Heart Ventricles Speckle tracking echocardiography 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Humans Radiology Nuclear Medicine and imaging In patient Subclinical infection medicine.diagnostic_test business.industry Myocardium Reproducibility of Results medicine.disease Confidence interval 030228 respiratory system Echocardiography Positron emission tomography Meta-analysis Cardiology Cardiology and Cardiovascular Medicine business Electrocardiography
Zdroj:	Echocardiography. 37:2061-2070
ISSN:	1540-8175 0742-2822
DOI:	10.1111/echo.14886
Popis:	BACKGROUND This meta-analysis aims to evaluate the utility of speckle tracking echocardiography (STE) as a tool to evaluate for cardiac sarcoidosis (CS) early in its course. Electrocardiography and echocardiography have limited sensitivity in this role, while advanced imaging modalities such as cardiac magnetic resonance (CMR) and 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) are limited by cost and availability. METHODS We compiled English language articles that reported left ventricular global longitudinal strain (LVGLS) or global circumferential strain (GCS) in patients with confirmed extra-cardiac sarcoidosis versus healthy controls. Studies that exclusively included patients with probable or definite CS were excluded. Continuous data were pooled as a standard mean difference (SMD), comparing sarcoidosis group with healthy controls. A random-effect model was adopted in all analyses. Heterogeneity was assessed using Q and I2 statistics. RESULTS Nine studies were included in our final analysis with an aggregate of 967 patients. LVGLS was significantly lower in the extra-cardiac sarcoidosis group as compared with controls, SMD -3.98, 95% confidence interval (CI): -5.32, -2.64, P
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b064943a7345e30deca6dabc7360eb44 https://doi.org/10.1111/echo.14886 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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