Reverse transcriptase meets DNA, again: Possible roles for transposable elements in host DNA repair

Autor:	John V. Moran, Thomas E. Wilson
Rok vydání:	2022
Předmět:	DNA Repair Retroelements DNA Transposable Elements RNA RNA-Directed DNA Polymerase General Biochemistry Genetics and Molecular Biology Introns
Zdroj:	Cell. 185(20)
ISSN:	1097-4172
Popis:	Retrotransposons are selfish genetic elements that encode an enzyme, reverse transcriptase (RT), which converts the element-encoded RNA into DNA prior to or during genomic integration. New studies provide compelling evidence that a bacterial group II intron-like RT has adapted enzymatic activities associated with RTs to function in host DNA repair.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b05c425d6f37bcd1d000e26244229153 https://pubmed.ncbi.nlm.nih.gov/36179663 Zobrazit plný text záznamu