Aggregation and crosslinking of poly(N,N-dimethylacrylamide)-b-pullulan double hydrophilic block copolymers
| Autor: | Jochen Willersinn, Bernhard V. K. J. Schmidt, Alexander Plucinski, Rafael de Lira, Rumiana Dimova |
|---|---|
| Přispěvatelé: | Molecular Biophysics |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Polymers and Plastics
biopolymers 02 engineering and technology 010402 general chemistry 01 natural sciences chemistry.chemical_compound Polymer chemistry Materials Chemistry Copolymer crosslinking Physical and Theoretical Chemistry chemistry.chemical_classification Aqueous solution Organic Chemistry Pullulan Polymer self-assembly 021001 nanoscience & nanotechnology Condensed Matter Physics Oxime 0104 chemical sciences Dilution block copolymers reversible addition fragmentation chain transfer (RAFT) chemistry Acrylamide Self-assembly 0210 nano-technology |
| Zdroj: | Macromolecular Chemistry and Physics, 221(13):2000053. WILEY-V C H VERLAG GMBH Macromolecular Chemistry and Physics |
| ISSN: | 1022-1352 |
| Popis: | The self-assembly of polymers is a major topic in current polymer chemistry. In here, the self-assembly of a pullulan based double hydrophilic block copolymer, namely pullulan-b-poly(N,N-dimethylacrylamide)-co-poly(diacetone acrylamide) (Pull-b-(PDMA-co-PDAAM)) is described. The hydrophilic block copolymer induces phase separation at high concentration in aqueous solution. Additionally, the block copolymer displays aggregates at lower concentration, which show a size dependence on concentration. In order to stabilize the aggregates, crosslinking via oxime formation is described, which enables preservation of aggregates at high dilution, in dialysis and in organic solvents. With adequate stability by crosslinking, double hydrophilic block copolymer (DHBC) aggregates open pathways for potential biomedical applications in the future. |
| Databáze: | OpenAIRE |
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