Synthesis and characterization of conductive flexible cellulose carbon nanohorn sheets for human tissue applications
| Autor: | Toshiyuki Nakamura, Taichi Nagahata, Takeshi Nishikawa, Ayano Satoh, Karthik Paneer Selvam, Mayuko Koreishi, Yoshimasa Nakamura, Kosuke Kato, Yasuhiko Hayashi |
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| Rok vydání: | 2020 |
| Předmět: |
lcsh:Medical technology
Materials science Scanning electron microscope Composite number Biomedical Engineering Medicine (miscellaneous) 02 engineering and technology 010402 general chemistry 01 natural sciences Carbon Nanohorns Biomaterials chemistry.chemical_compound symbols.namesake Ultimate tensile strength Cellulose Fourier transform infrared spectroscopy Bio-compatible Composites Biomaterial 021001 nanoscience & nanotechnology 0104 chemical sciences lcsh:R855-855.5 chemistry Chemical engineering Transmission electron microscopy Ceramics and Composites symbols 0210 nano-technology Raman spectroscopy Skin sensitization Research Article |
| Zdroj: | Biomaterials Research, Vol 24, Iss 1, Pp 1-12 (2020) Biomaterials Research |
| Popis: | Background Conductive sheets of cellulose and carbon nanomaterials and its human skin applications are an interesting research aspect as they have potential for applications for skin compatibility. Hence it is needed to explore the effects and shed light on these applications. Method To fabricate wearable, portable, flexible, lightweight, inexpensive, and biocompatible composite materials, carbon nanohorns (CNHs) and hydroxyethylcellulose (HEC) were used as precursors to prepare CNH-HEC (Cnh-cel) composite sheets. Cnh-cel sheets were prepared with different loading concentrations of CNHs (10, 20 50,100 mg) in 200 mg cellulose. To fabricate the bio-compatible sheets, a pristine composite of CNHs and HEC was prepared without any pretreatment of the materials. Results The obtained sheets possess a conductivity of 1.83 × 10− 10 S/m and bio-compatible with human skin. Analysis for skin-compatibility was performed for Cnh-cel sheets by h-CLAT in vitro skin sensitization tests to evaluate the activation of THP-1 cells. It was found that THP-1 cells were not activated by Cnh-cel; hence Cnh-cel is a safe biomaterial for human skin. It was also found that the composite allowed only a maximum loading of 100 mg to retain the consistent geometry of free-standing sheets of Conclusion It can be concluded that cellulose and CNHs sheets are conductive and compatible to human skin applications. |
| Databáze: | OpenAIRE |
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