Synthesis and biological evaluation of new symmetric curcumin derivatives

Autor:	Govindharaj Banuppriya, Maruthan Kirubavathi, Vediappen Padmini, Rajendran Sribalan
Rok vydání:	2015
Předmět:	Antioxidant Curcumin medicine.drug_class medicine.medical_treatment Clinical Biochemistry Pharmaceutical Science Biochemistry Anti-inflammatory Antioxidants chemistry.chemical_compound Structure-Activity Relationship Cell Line Tumor Drug Discovery medicine Structure–activity relationship Animals Humans Cytotoxicity Molecular Biology Biological evaluation Cell Death Dose-Response Relationship Drug Molecular Structure Cytotoxins Organic Chemistry Anti-Inflammatory Agents Non-Steroidal Serum Albumin Bovine In vitro chemistry Molecular Medicine Cattle
Zdroj:	Bioorganicmedicinal chemistry letters. 25(19)
ISSN:	1464-3405
Popis:	A series of novel curcumin bisacetamides aiming of enriching their biological activities have been synthesized. The synthesized compounds were screened for their in vitro antioxidant, anti-inflammatory and cytotoxic activities. All the compounds exhibited potent to good anti-inflammatory, antioxidant and noteworthy cytotoxic activities.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b054b531cc0df0c1f144c2a65d6ba765 https://pubmed.ncbi.nlm.nih.gov/26264500 Zobrazit plný text záznamu Full Text from ScienceDirect