Emergence of Candida auris in Russia
| Autor: | C. Lass-Floerl, Mitrokhin Sd, I. V. Churkina, O.E. Orlova, A.S. Shkoda, Elizabeth M. Johnson, E. P. Barantsevich, N. E. Barantsevich, Neil Woodford, E.V. Shlyakhto |
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| Rok vydání: | 2018 |
| Předmět: |
Microbiology (medical)
Antifungal Adult Male medicine.medical_specialty South asia Antifungal Agents Adolescent medicine.drug_class Microbial Sensitivity Tests DNA Ribosomal Moscow law.invention Young Adult law Risk Factors Internal medicine DNA Ribosomal Spacer medicine Cluster Analysis Humans In patient Internal transcribed spacer DNA Fungal Phylogeny Aged Candida Aged 80 and over Cross Infection Phylogenetic tree business.industry Candidemia General Medicine Sequence Analysis DNA Middle Aged Intensive care unit Survival Analysis Intensive Care Units Infectious Diseases Candida auris RNA Ribosomal Female business |
| Zdroj: | The Journal of hospital infection. 102(4) |
| ISSN: | 1532-2939 |
| Popis: | Summary This paper reports the emergence of Candida auris infections in an intensive care unit at a hospital in Moscow. Forty-nine cases were diagnosed in 2016–2017, and the risk factors and antifungal susceptibilities are described. The 30-day all-cause mortality for 19 bloodstream infections in patients who did not receive appropriate antifungal therapy was 42.1%. Phylogenetic analysis of the internal transcribed spacer and D1–D2 regions and K143R substitution in the ERG11 gene indicated that the studied C. auris strains were of South Asian origin. This first reported series of C. auris infections in Russia demonstrates the rapid dissemination of this species, and the need for international surveillance and control measures. |
| Databáze: | OpenAIRE |
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