Diffuse Alveolar Septal Amyloidosis With Wild-Type Transthyretin With Spontaneous Lung Hematoma
| Autor: | Yoshitane Tsukamoto, Shohei Matsuo, Emiko Tomita, Akinori Akashi, Kenjiro Fukuhara |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Lung Diseases
Male Pulmonary and Respiratory Medicine Amyloid Pathology medicine.medical_specialty 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Hematoma Atrial Fibrillation medicine Humans Prealbumin cardiovascular diseases Aged Heart Failure Amyloid Neuropathies Familial Lung biology business.industry Amyloidosis nutritional and metabolic diseases Atrial fibrillation respiratory system medicine.disease Pulmonary Alveoli Transthyretin Amyloid Neuropathy medicine.anatomical_structure 030228 respiratory system Cardiac amyloidosis Heart failure cardiovascular system biology.protein Surgery Cardiology and Cardiovascular Medicine business |
| Zdroj: | The Annals of Thoracic Surgery. 107:e131-e133 |
| ISSN: | 0003-4975 |
| DOI: | 10.1016/j.athoracsur.2018.05.096 |
| Popis: | We experienced a mass formation in the right lower lobe in a patient with cardiac amyloidosis and heart failure. Radiologic findings of the chest showed no abnormality except a mass. The patient had non-valvular atrial fibrillation and was taking edoxaban. Surgical resection of the mass revealed a hematoma. Further pathologic evaluation revealed diffuse alveolar septal amyloidosis with transthyretin (ATTR). The genetic testing found no mutation in the TTR gene. Therefore, systemic wild-type TTR amyloidosis (ATTRwt) was confirmed. Alveolar septal ATTRwt is rare and patient had alveolar septal ATTRwt with spontaneous lung hematoma. |
| Databáze: | OpenAIRE |
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