Reproducible Matrix Deposition for MALDI MSI Based on Open-Source Software and Hardware
| Autor: | Dieter Staab, Markus Stoeckli |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Reproducibility
Information Dissemination business.industry Chemistry Open design Reproducibility of Results Equipment Design Open source software engineering.material Maldi msi Rats Specimen Handling Open source Software Coating Structural Biology Spectrometry Mass Matrix-Assisted Laser Desorption-Ionization engineering Animals Pharmacokinetics Sample preparation business Spectroscopy Computer hardware |
| Zdroj: | Journal of the American Society for Mass Spectrometry. 26:911-914 |
| ISSN: | 1044-0305 |
| DOI: | 10.1007/s13361-015-1099-9 |
| Popis: | The new open-source software and hardware matrix deposition device named iMatrixSpray was optimized and specified for homogeneity, reproducibility, and sensitivity in MS imaging experiments. The results confirm the design claims, with the device delivering uniform coatings with a constant quality from experiment to experiment. The robustness in combination with the open design allows developing and sharing of matrix deposition and sample preparation protocols between labs. This tool therefore enables researchers to enter the field of MALDI MSI without previous experience in matrix coating. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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