Risk factors and early prediction of clinical deterioration and mortality in adult COVID ‐19 inpatients: an Australian tertiary hospital experience
| Autor: | Hui Yin Lim, Kay Weng Choy, Rowena Brook, Prahlad Ho |
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| Rok vydání: | 2022 |
| Předmět: |
Male
medicine.medical_specialty Tertiary Care Centers chemistry.chemical_compound Tocilizumab Risk Factors Interquartile range Internal medicine Diabetes mellitus Internal Medicine medicine Humans Hospital Mortality Aged Retrospective Studies Aged 80 and over Inpatients Clinical Deterioration biology SARS-CoV-2 business.industry Medical record Australia Area under the curve COVID-19 Retrospective cohort study Middle Aged medicine.disease Triage Ferritin C-Reactive Protein chemistry Ferritins biology.protein Female business |
| Zdroj: | Internal Medicine Journal. 52:550-558 |
| ISSN: | 1445-5994 1444-0903 |
| Popis: | BACKGROUND: Early recognition of severe COVID-19 is essential for timely patient triage. AIMS: We aim to report clinical and laboratory findings and patient outcomes at a tertiary hospital in Melbourne, Australia. METHODS: This is a retrospective study of adult inpatients with COVID-19 admitted to Northern Health from March to September 2020. Data were extracted from electronic medical records. RESULTS: Key admission data was available for 182 patients (median age 67.0 years (interquartile range, 47.9-83.1; 51.1% female). 56 (30.8%) were from residential care. 117 (64.3%) patients were assigned Goals-of-Patient-Care (GOPC) A or B and 65 (35.7%) GOPC C or D. Comorbidities were present in 135 patients (74.2%). 63.2% of patients received antibiotics, 6.6% had antivirals, 45.6% received systemic glucocorticoid and 3.3% had tocilizumab. 56 (30.8%) developed clinical deterioration (24 requiring ventilation, 21 receiving critical care, 34 died). Overall, in-hospital clinical deterioration was significantly associated with older age (p |
| Databáze: | OpenAIRE |
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