Retrospective study on transmissible viral proventriculitis and chicken proventricular necrosis virus (CPNV) in the UK
| Autor: | N Wali, Simone de Brot, Aline Padilha de Fraga, Cristina Garcia-Rueda, Alex Schock, Llorenç Grau-Roma, Miquel Nofrarías, Natàlia Majó |
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| Přispěvatelé: | Producció Animal, Sanitat Animal |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
040301 veterinary sciences Stomach Diseases 610 Medicine & health Disease Biology Virus 0403 veterinary science Food Animals Epidemiology medicine Birnaviridae Animals Pathogen Phylogeny Poultry Diseases Retrospective Studies General Immunology and Microbiology Proventriculitis 630 Agriculture Reverse Transcriptase Polymerase Chain Reaction Sequence Analysis RNA 0402 animal and dairy science Broiler Retrospective cohort study 04 agricultural and veterinary sciences Birnaviridae Infections 040201 dairy & animal science Virology Chicken proventricular necrosis virus RNA Viral 570 Life sciences biology Animal Science and Zoology Proventriculus Chickens Sequence Alignment |
| Zdroj: | Grau-Roma, Llorenç; Schock, Alex; Nofrarías, Miquel; Ali Wali, Nabil; de Fraga, Aline Padilha; Garcia-Rueda, Cristina; De Brot, Simone; Majó, Natalia (2020). Retrospective study on transmissible viral proventriculitis and chicken proventricular necrosis virus (CPNV) in the UK. Avian pathology, 49(1), pp. 99-105. Taylor & Francis 10.1080/03079457.2019.1677856 IRTA Pubpro. Open Digital Archive Institut de Recerca i Tecnologia Agroalimentàries (IRTA) |
| DOI: | 10.1080/03079457.2019.1677856 |
| Popis: | Chicken proventricular necrosis virus (CPNV) is a recently described birnavirus, which has been proposed to be the cause of transmissible viral proventriculitis (TVP). The understanding of the epidemiology of both the virus and the disease is very limited. A retrospective investigation on TVP and CPNV in broiler chicken submissions from the UK from between 1994 and 2015 was performed with the aims of assessing the longitudinal temporal evolution of TVP and CPNV, and to review the histological proventricular lesions in the studied chickens. Ninety-nine of the 135 included submissions (73.3%) fulfilled the TVP-diagnostic criteria, while the remaining 36 submissions (26.7%) displayed only lymphocytic proventriculitis (LP). The first detection of CPNV by PCR dated from 2009. Results showed a rise in the number of both TVP and positive CPNV RT-PCR submissions from 2009 with a peak in 2013, suggesting that they may be an emerging or re-emerging disease and pathogen, respectively. Twenty-two out of the 99 submissions displaying TVP lesions (22%) and four out of the 36 (11%) submissions with LP gave positive CPNV RT-PCR results, further supporting the association between CPNV and TVP and confirming that CPNV is present in a low proportion of proventriculi that do not fulfil the TVP-diagnostic criteria. In addition, intranuclear inclusion bodies were observed in 22 of the submissions with TVP. The vast majority of these cases (21 of 22, 96%) gave negative CPNV RT-PCR results, raising the question of whether a virus other than CPNV is responsible for some of these TVP-affected cases.RESEARCH HIGHLIGHTSTVP and CPNV have been present in British broilers since at least 1994 and 2009, respectively.TVP and CPNV seem to be an emerging and re-emerging disease and pathogen, respectively.CPNV was detected in proventriculi with both TVP and LP-lesions.Viruses other than CPNV may be responsible for some TVP-affected cases. info:eu-repo/semantics/acceptedVersion |
| Databáze: | OpenAIRE |
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