Pregnancy does not affect fecal calprotectin concentration in healthy women
| Autor: | Anna Fábián, Klaudia Farkas, Éva Pallagi Kunstár, Tamás Molnár, Ábel Altorjay, Ágnes Milassin, Rutka Mariann, Mária Krizsán, Ádám Szulcsán, Renáta Bor, Mónika Szűcs, Anita Bálint, Anna Berényi, Andrea Csonka, Zoltán Szepes, Attila Pál |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
medicine.medical_specialty Disease Inflammatory bowel disease Gastroenterology 03 medical and health sciences Feces 0302 clinical medicine Pregnancy Internal medicine Medicine Humans Prospective Studies Prospective cohort study reproductive and urinary physiology medicine.diagnostic_test business.industry medicine.disease Inflammatory Bowel Diseases Ulcerative colitis digestive system diseases Endoscopy C-Reactive Protein 030220 oncology & carcinogenesis 030211 gastroenterology & hepatology Female Calprotectin business Leukocyte L1 Antigen Complex Biomarkers |
| Zdroj: | The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology. 28(3) |
| ISSN: | 2148-5607 |
| Popis: | Background/Aims: Noninvasive activity markers are extremely important in conditions, such as pregnancy, when endoscopy is not recommended. The aim of this prospective study was to determine fecal calprotectin (FC) concentrations in healthy non-pregnant and pregnant women and in patients with inflammatory bowel disease (IBD). Materials and Methods: Healthy pregnant and non-pregnant women and patients with active and inactive IBD were prospectively enrolled in this study. Demographic and clinical parameters and clinical disease activity scores in patients with IBD were recorded. Blood and stool samples of every patient were obtained to determine C-reactive protein and FC levels. FC levels were measured with a quantitative lateral flow assay. Results: One hundred and thirty-five subjects were enrolled in the study (24 non-pregnant and 48 pregnant healthy women, 40 non-pregnant patients with active IBD and 23 non-pregnant patients with inactive IBD). FC was significantly higher in active IBD patients than in pregnant (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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