New Insights into the Mammalian Egg Zona Pellucida
| Autor: | Carla Moros-Nicolás, Manuel Avilés, Mª José Izquierdo-Rico, María Jiménez-Movilla, Paula Cots-Rodríguez, Pascale Chevret, Leopoldo González-Brusi, Blanca Algarra |
|---|---|
| Přispěvatelé: | Ecologie et évolution des populations, Département écologie évolutive [LBBE], Laboratoire de Biométrie et Biologie Evolutive - UMR 5558 (LBBE), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique (Inria)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique (Inria)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Laboratoire de Biométrie et Biologie Evolutive - UMR 5558 (LBBE), Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique (Inria)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS) |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Male
0301 basic medicine zona pellucida Cell Communication Review [SDV.BID.SPT]Life Sciences [q-bio]/Biodiversity/Systematics Phylogenetics and taxonomy lcsh:Chemistry 0302 clinical medicine Zona pellucida lcsh:QH301-705.5 Spectroscopy ComputingMilieux_MISCELLANEOUS Mammals chemistry.chemical_classification 030219 obstetrics & reproductive medicine [SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE] Gene Expression Regulation Developmental Embryo General Medicine Polyspermy Spermatozoa Computer Science Applications Cell biology Protein Transport medicine.anatomical_structure Female pseudogenization Biology Zona Pellucida Glycoproteins Catalysis Evolution Molecular Inorganic Chemistry 03 medical and health sciences Molecular evolution medicine Animals Gene family Physical and Theoretical Chemistry Molecular Biology Gene Ovum [SDV.GEN.GPO]Life Sciences [q-bio]/Genetics/Populations and Evolution [q-bio.PE] molecular evolution Organic Chemistry Oocyte 030104 developmental biology lcsh:Biology (General) lcsh:QD1-999 chemistry composition Oocytes ZP [SDE.BE]Environmental Sciences/Biodiversity and Ecology Glycoprotein Biomarkers |
| Zdroj: | International Journal of Molecular Sciences International Journal of Molecular Sciences, 2021, 22 (6), pp.3276. ⟨10.3390/ijms22063276⟩ International Journal of Molecular Sciences, MDPI, 2021, 22 (6), pp.3276. ⟨10.3390/ijms22063276⟩ International Journal of Molecular Sciences, Vol 22, Iss 3276, p 3276 (2021) |
| ISSN: | 1661-6596 1422-0067 |
| DOI: | 10.3390/ijms22063276⟩ |
| Popis: | Mammalian oocytes are surrounded by an extracellular coat called the zona pellucida (ZP), which, from an evolutionary point of view, is the most ancient of the coats that envelope vertebrate oocytes and conceptuses. This matrix separates the oocyte from cumulus cells and is responsible for species-specific recognition between gametes, preventing polyspermy and protecting the preimplantation embryo. The ZP is a dynamic structure that shows different properties before and after fertilization. Until very recently, mammalian ZP was believed to be composed of only three glycoproteins, ZP1, ZP2 and ZP3, as first described in mouse. However, studies have revealed that this composition is not necessarily applicable to other mammals. Such differences can be explained by an analysis of the molecular evolution of the ZP gene family, during which ZP genes have suffered pseudogenization and duplication events that have resulted in differing models of ZP protein composition. The many discoveries made in recent years related to ZP composition and evolution suggest that a compilation would be useful. Moreover, this review analyses ZP biosynthesis, the role of each ZP protein in different mammalian species and how these proteins may interact among themselves and with other proteins present in the oviductal lumen. |
| Databáze: | OpenAIRE |
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