Alterations in the RNA, protein and free amino acid level of the liver of the garden lizard, calotes versicolor, during aging and partial hepatectomy

Autor: B.K. Patnaik, K.L. Rao
Rok vydání: 1971
Předmět:
Zdroj: Experimental Gerontology. 6:397-404
ISSN: 0531-5565
DOI: 10.1016/0531-5565(71)90019-2
Popis: The relative RNA content (mg/g wet wt.) in the liver of Calotes versicolor rises till the lizards weight about 15 g and then declines with increasing age. Total RNA (mg/whole liver) reaches the peak at 32–38 g of bodyweight and remains constant thereafter. The protein concentration (mg/g wet wt.) increases more rapidly up to 48 g of bodyweight and then slowly increases during the later half of the lifespan. The total protein (mg/whole liver) also shows the same trend. The specific free amino acid level (mg/g wet wt.) shows a decline till the lizards weigh 32–38 g and thereafter remains at a constant level. Total free amino acid pool (mg/ whole liver) increases more significantly up to 35–38 g bodyweight followed by a slow rise. Partial hepatectomy leads to an increase in RNA, Protein and free amino acid content of the liver at 4 hr after operation followed by a decrease at 24 hr. The changes in protein and free amino acid content were more significant in younger lizards than the older ones.
Databáze: OpenAIRE