Alterations in the RNA, protein and free amino acid level of the liver of the garden lizard, calotes versicolor, during aging and partial hepatectomy
Autor: | B.K. Patnaik, K.L. Rao |
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Rok vydání: | 1971 |
Předmět: |
Male
Aging medicine.medical_specialty Biology Partial hepatectomy Free amino Biochemistry Endocrinology Internal medicine Genetics medicine Animals Hepatectomy Amino Acids Molecular Biology Acid level Rna protein Body Weight Whole liver Proteins RNA Lizards Cell Biology Liver Regeneration Liver Protein Biosynthesis Garden lizard Calotes versicolor |
Zdroj: | Experimental Gerontology. 6:397-404 |
ISSN: | 0531-5565 |
DOI: | 10.1016/0531-5565(71)90019-2 |
Popis: | The relative RNA content (mg/g wet wt.) in the liver of Calotes versicolor rises till the lizards weight about 15 g and then declines with increasing age. Total RNA (mg/whole liver) reaches the peak at 32–38 g of bodyweight and remains constant thereafter. The protein concentration (mg/g wet wt.) increases more rapidly up to 48 g of bodyweight and then slowly increases during the later half of the lifespan. The total protein (mg/whole liver) also shows the same trend. The specific free amino acid level (mg/g wet wt.) shows a decline till the lizards weigh 32–38 g and thereafter remains at a constant level. Total free amino acid pool (mg/ whole liver) increases more significantly up to 35–38 g bodyweight followed by a slow rise. Partial hepatectomy leads to an increase in RNA, Protein and free amino acid content of the liver at 4 hr after operation followed by a decrease at 24 hr. The changes in protein and free amino acid content were more significant in younger lizards than the older ones. |
Databáze: | OpenAIRE |
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