Therapeutic effect of methane and its mechanism in disease treatment
| Autor: | Xuejun Sun, Bradley P. Ander, Ke Ning, Zhouheng Ye |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Methanogenesis Apoptosis Review Antioxidants General Biochemistry Genetics and Molecular Biology Methane 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Ischemia Humans General Pharmacology Toxicology and Pharmaceutics Methane production Disease treatment Inflammation chemistry.chemical_classification Carbon atom General Veterinary Mechanism (biology) General Medicine Marsh gas 030104 developmental biology Hydrocarbon chemistry Reperfusion Injury 030220 oncology & carcinogenesis Environmental chemistry |
| Zdroj: | J Zhejiang Univ Sci B |
| ISSN: | 1862-1783 1673-1581 |
| DOI: | 10.1631/jzus.b1900629 |
| Popis: | Methane is the simplest hydrocarbon, consisting of one carbon atom and four hydrogen atoms. It is abundant in marsh gas, livestock rumination, and combustible ice. Little is known about the use of methane in human disease treatment. Current research indicates that methane is useful for treating several diseases including ischemia and reperfusion injury, and inflammatory diseases. The mechanisms underlying the protective effects of methane appear primarily to involve anti-oxidation, anti-inflammation, and anti-apoptosis. In this review, we describe the beneficial effects of methane on different diseases, summarize possible mechanisms by which methane may act in these conditions, and discuss the purpose of methane production in hypoxic conditions. Then we propose several promising directions for the future research. |
| Databáze: | OpenAIRE |
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