The Effect of Long Term Phenothiazine Therapy on Plasma Prolactin
| Autor: | W. D. Boyd, A. R. Boyns, J. R. Hamilton, R. G. Wilson, A. P. M. Forrest, E. N. Cole, K. Griffiths |
|---|---|
| Rok vydání: | 1975 |
| Předmět: |
medicine.medical_specialty
Chlorpromazine Radioimmunoassay Breast Neoplasms Thioridazine Growth hormone 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Pregnancy Phenothiazine Internal medicine Humans Medicine Breast 030212 general & internal medicine Aged Antiserum Palpation business.industry Mental Disorders Galactorrhea Plasma prolactin Prolactin 030227 psychiatry Psychiatry and Mental health Endocrinology chemistry Growth Hormone Female business Antipsychotic Agents medicine.drug |
| Zdroj: | British Journal of Psychiatry. 127:71-74 |
| ISSN: | 1472-1465 0007-1250 |
| DOI: | 10.1192/bjp.127.1.71 |
| Popis: | SummaryPlasma prolactin has been estimated in 69 psychiatric in-patients receiving either thioridazine (20–300 mg./day) or chlorpromazine (50–200 mg./day) or other phenothiazines. A homologous radioimmuno-assay was used which depends on an antiserum to human amniotic prolactin. Prolactin levels were significantly increased in these patients compared with control patients, and were dose related. Simultaneous estimation of growth hormone revealed normal levels. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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