Effect of tetracycline on intestinal absorption of various nutrients by the rat
| Autor: | M. E. Shils, S. D. J. Yeh |
|---|---|
| Rok vydání: | 1966 |
| Předmět: |
medicine.medical_specialty
Tetracycline Iron Oleic Acids Urine Absorption (skin) Kidney General Biochemistry Genetics and Molecular Biology Intestinal absorption Excretion chemistry.chemical_compound Internal medicine medicine Animals Cyanocobalamin Triolein Vitamin B12 Xylose Iron Isotopes Rats Endocrinology chemistry Intestinal Absorption Liver lipids (amino acids peptides and proteins) Digestive System medicine.drug |
| Zdroj: | Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 123(2) |
| ISSN: | 0037-9727 |
| Popis: | SummaryTetracycline administration to adult rats (250 mg per kg i.m.) was associated with impaired intestinal absorption of fat (as 131I triolein) fatty acids (as 131I oleic) and radioactive iron. The jejunal mucosa of the treated animals was microscopically normal and without lipid accumulation. D-xylose absorption appeared to be increased as the result of tetracycline treatment since urinary excretion was significantly greater than that of control. Vitamin B12 absorption was not affected. Possible mechanisms accounting for this differential effect are discussed. |
| Databáze: | OpenAIRE |
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