Popis: |
Cyclosporin, combined with other agents, is an immunosuppressive agent approved for prophylaxis of renal transplant rejection. In experimental studies, cyclosporin has been shown to inhibit smooth muscle cell proliferation in the vascular response to injury. 1,2 Similar experimental results have been observed with systemic use of rapamycin. 3,4 The aim of this clinical investigation was to test the hypothesis that systemic immunosuppression therapy inhibits in-stent restenosis in renal transplant patients with coronary artery disease treated with stenting. |