Comprehensive Cardiovascular Magnetic Resonance Diastolic Dysfunction Grading Shows Very Good Agreement Compared With Echocardiography
Autor: | Eva Maret, Andreas Sigfridsson, Gert Reiter, Joao G. Ramos, Ning Jin, Alexander Fyrdahl, Martin Ugander, Ursula Reiter, Peder Sörensson, Maria J. Eriksson, Simon Thalén, Kenneth Caidahl, Björn Wieslander |
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Rok vydání: | 2020 |
Předmět: |
Male
medicine.medical_specialty Magnetic Resonance Spectroscopy Diastole 030204 cardiovascular system & hematology 030218 nuclear medicine & medical imaging Ventricular Dysfunction Left 03 medical and health sciences 0302 clinical medicine Cohen's kappa Predictive Value of Tests Interquartile range medicine.artery Internal medicine Humans Medicine Radiology Nuclear Medicine and imaging cardiovascular diseases Grading (education) Aged medicine.diagnostic_test business.industry Magnetic resonance imaging Blood flow Middle Aged Confidence interval Echocardiography Pulmonary artery cardiovascular system Cardiology Female Cardiology and Cardiovascular Medicine business |
Zdroj: | JACC: Cardiovascular Imaging. 13:2530-2542 |
ISSN: | 1936-878X |
Popis: | Objectives The aims of this study were to develop a comprehensive cardiovascular magnetic resonance (CMR) approach to diastolic dysfunction (DD) grading and to evaluate the accuracy of CMR in the diagnosis of DD compared with echocardiography. Background Left ventricular DD is routinely assessed using echocardiography. Methods Consecutive clinically referred patients (n = 46; median age 59 years; interquartile range: 46 to 68 years; 33% women) underwent both conventional echocardiography and CMR. CMR diastolic transmitral velocities (E and A) and myocardial tissue velocity (e′) were measured during breath-hold using a validated high–temporal resolution radial sector-wise golden-angle velocity-encoded sequence. CMR pulmonary artery pressure was estimated from 4-dimensional flow analysis of blood flow vortex duration in the pulmonary artery. CMR left atrial volume was measured using the biplane long-axis area-length method. Both CMR and echocardiographic data were used to perform blinded grading of DD according to the 2016 joint American and European recommendations. Results Grading of DD by CMR agreed with that by echocardiography in 43 of 46 cases (93%), of which 9% were normal, 2% indeterminate, 63% grade 1 DD, 4% grade 2 DD, and 15% grade 3 DD. There was a very good categorical agreement, with a weighted Cohen kappa coefficient of 0.857 (95% confidence interval: 0.73 to 1.00; p Conclusions A comprehensive CMR protocol for grading DD encompassing diastolic blood and myocardial velocities, estimated pulmonary artery pressure, and left atrial volume showed very good agreement with echocardiography. |
Databáze: | OpenAIRE |
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