A probabilistic atlas of the human ventral tegmental area (VTA) based on 7 Tesla MRI data

Autor: Birte U. Forstmann, Laura Fontanesi, Bernhard Hommel, Pierre-Louis Bazin, Martijn J. Mulder, Anne C. Trutti
Přispěvatelé: Psychology Other Research (FMG), FMG, Brain and Cognition, Brein en Cognitie (Psychologie, FMG), Experimental Psychology (onderzoeksprogramma PF), Helmholtz Institute, Leerstoel Kenemans
Rok vydání: 2020
Předmět:
Zdroj: Brain Structure & Function
Brain Structure and Function, 226(4), 1155-1167. Springer Verlag
Brain Structure and Function
Brain Structure & Function, 226(4), 1155. Springer Verlag
Brain structure & function
ISSN: 1863-2661
1863-2653
Popis: Functional magnetic resonance imaging (fMRI) BOLD signal is commonly localized by using neuroanatomical atlases, which can also serve for region of interest analyses. Yet, the available MRI atlases have serious limitations when it comes to imaging subcortical structures: only 7% of the 455 subcortical nuclei are captured by current atlases. This highlights the general difficulty in mapping smaller nuclei deep in the brain, which can be addressed using ultra-high field 7 Tesla (T) MRI. The ventral tegmental area (VTA) is a subcortical structure that plays a pivotal role in reward processing, learning and memory. Despite the significant interest in this nucleus in cognitive neuroscience, there are currently no available, anatomically precise VTA atlases derived from 7 T MRI data that cover the full region of the VTA. Here, we first provide a protocol for multimodal VTA imaging and delineation. We then provide a data description of a probabilistic VTA atlas based on in vivo 7 T MRI data.
Databáze: OpenAIRE