The Effects of Supplementation with a Mixture of Arginine, Glutamine, and β-hydroxy β-methylbutyrate on the Healing of Colon Anastomoses
| Autor: | Gaye Seker, Melih Akinci, Jülide Ergil, E. Arık, D Seker, Ginis Z, Derya Özkan, A Yalcindag |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
chemistry.chemical_classification
medicine.medical_specialty Arginine business.industry Beta hydroxy beta methylbutyrate General Medicine Anastomosis Surgery Amino acid Glutamine Cecum Hydroxyproline chemistry.chemical_compound Endocrinology medicine.anatomical_structure chemistry Internal medicine medicine business Wound healing |
| Zdroj: | Scopus-Elsevier |
| ISSN: | 0001-5458 |
| DOI: | 10.1080/00015458.2013.11680961 |
| Popis: | Background : Several researchers have investigated how wound healing is effected by supplementation with each of the following amino acids: arginine (Arg), glutamine (Glu), and β-hydroxy β-methylbutyrate (HMB). This research investigates how a combination of these amino acids improves the wound healing associated with anastomoses. Methods : We tested the effects of a combination of Arg, Glu, and HMB on the healing of colon anastomoses in 50 male rats. We randomly divided the animals into two equal groups. In each animal, the cecum was transected from its midpoint to create an end-to end anastomosis. During the first postoperative week, Group 1 (G1) animals were fed standard chow, and Group 2 (G2) animals were fed standard chow plus a ready-to-use supplement that contained a mixture of Arg, Glu, and HMB. At the end of the week, all of the rats were sacrificed, and a cecum segment containing the anastomosis line was resected. Bursting pressure and tissue hydroxyproline were measured for all animals.... |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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