HIV-1 infection in HIV-1 enzyme-linked immunoassay seronegative patients in Kinshasa, Zaire
| Autor: | B. Kapita, Henry Francis, W. L. Heyward, G van der Groen, R. Colebunders, I. Lebughe, Peter Piot, T C Quinn, Mavunza Mpaka Duma |
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| Rok vydání: | 1990 |
| Předmět: |
Adult
Male HIV Antigens Blotting Western Human immunodeficiency virus (HIV) Enzyme-Linked Immunosorbent Assay Dermatology medicine.disease_cause Serology 03 medical and health sciences 0302 clinical medicine Acquired immunodeficiency syndrome (AIDS) Antigen Western blot HIV Seropositivity medicine Humans Pharmacology (medical) 030212 general & internal medicine False Negative Reactions 030505 public health biology medicine.diagnostic_test business.industry Public Health Environmental and Occupational Health virus diseases AIDS Serodiagnosis medicine.disease Serum samples Virology Infectious Diseases Immunology biology.protein Democratic Republic of the Congo HIV-1 Enzyme linked immunoassay Female Antibody 0305 other medical science business |
| Zdroj: | International journal of STDAIDS. 1(5) |
| ISSN: | 0956-4624 |
| Popis: | Serum samples of 62 African patients who had clinical manifestations of HIV-1 infection but were seronegative for HIV-1 by ELISA (Organon) were subsequently further tested by another HIV-1 ELISA test (Wellcozyme), HIV-1 IgG Western blot, HIV-1 antigen detection and HIV-2 ELISA. Patients' lymphocytes were cultured for HIV-1 and 2. Because of limited quantities of serum available all tests were not performed on all samples. Seven (26%) of 27 sera of patients meeting the WHO clinical case definition of AIDS were Western-blot-positive. In contrast, of 35 patients' sera with possible HIV related disease, only one (3%) was Western blot positive ( P=0.02) and none of 75 sera from HIV-1 ELISA (Organon) seronegative blood donors ( P |
| Databáze: | OpenAIRE |
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