The relationship between benign paroxysmal positional vertigo and thyroid autoimmunity

Autor:	Tekin Yildirim, Kamran Sari, Mahmut Özkiriş, Reha Aydin, Hasan Börekci, İbrahim Akin
Rok vydání:	2015
Předmět:	Adult Male medicine.medical_specialty Benign paroxysmal positional vertigo Vestibular disorders Posture Thyroid Gland Autoimmunity Audiology Gastroenterology Internal medicine Vertigo otorhinolaryngologic diseases Humans Medicine Benign Paroxysmal Positional Vertigo Normal control Autoantibodies Retrospective Studies biology business.industry Thyroiditis Autoimmune General Medicine Middle Aged medicine.disease biology.organism_classification Anti-thyroid autoantibodies Otorhinolaryngology Positional vertigo Thyroid autoimmunity Etiology Female sense organs business
Zdroj:	Acta Oto-Laryngologica. 135:754-757
ISSN:	1651-2251 0001-6489
Popis:	Although there have been few studies concerning BPPV and thyroid autoimmunity and a positive relation was found between them, this study didn't find any relation between BPPV and thyroid autoimmunity. IT is thought that further large-scale studies must be done to clarify the relation.Benign paroxysmal positional vertigo (BPPV) consists of ∼ 20% of vestibular disorders. Self-limited rotatory nystagmus with positional vertigo are the main findings of BPPV. Although canalolithiasis theory was confirmed by demonstrating freely floating debris in the endolymph of the posterior semicircular channel in following studies, currently, the etiology hasn't been explained totally. This study investigated the relation of BPPV and thyroid autoimmunity evaluated via measurement of serum thyroid autoantibodies.Fifty patients (37 female, 13 male) with BPPV (BPPV group), 52 patients (40 female, 12 male) with non-BPPV vertigo (non-BPPV group) and 60 otherwise normal control (38 female, 22 male) samples were enrolled in the study. All samples of BPPV, non-BPPV groups and controls had undergone a cochleovestibular test following thorough ENT examination. After blood samples were drawn from each subject, thyroid-stimulating hormone (TSH), anti-thyroid peroxidase antibody (TPO-Ab) and anti-thyroglobulin antibody (TG-Ab) levels were measured accordingly.In the study, eight patients of the BPPV group (16%) had a high thyroid antibody level. In the non-BPPV group, six patients (11.5%) had elevated thyroid antibodies. In the control group, 15 patients (25%) had elevated thyroid antibodies. TSH values of all subjects were detected to be within normal range. No statistical difference was found between the groups with respect to TG-Ab and TPO-Ab values (p-values = 0.729 and 0.812, respectively).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b004cfd7ba7fb320f45e954b68bbd581 https://doi.org/10.3109/00016489.2015.1021932 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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