Results of Exposure of Strain G3H Mice to Chloroform

Autor:	Margaret K. Deringer, W. E. Heston, Thelma B. Dunn
Rok vydání:	1953
Předmět:	Mice Inbred C3H medicine.medical_specialty Chloroform Strain (chemistry) Chemistry Kidney pathology Physiology Liter Kidney General Biochemistry Genetics and Molecular Biology Surgery Accidental exposure Lesion Mice chemistry.chemical_compound medicine Animals medicine.symptom
Zdroj:	Experimental Biology and Medicine. 83:474-479
ISSN:	1535-3699 1535-3702
DOI:	10.3181/00379727-83-20389
Popis:	Summary1. Exposure of strain C3H mice to air containing approximately 5 mg of chloroform per liter for one, 2, or 3 hours resulted in lesions of the kidneys of all of the males but in none of the females. Histologic details of this lesion were described. 2. The lesion found in the male animals in this experiment was similar to that exhibited by the males of strains C3H, C3Hf, A, and HR, some of which died immediately after an accidental exposure to chloroform and some in the months following the exposure. 3. A genetic difference was apparent in that whereas strains C3H, C3Hf, A, and HR were susceptible, strains C57BL, C57BR/cd, C57L, and ST were resistant to the accidental exposure.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::affee1a9962be9bdb51de31442f1f031 https://doi.org/10.3181/00379727-83-20389 Zobrazit plný text záznamu