High-sensitivity four-layer polymer fiber-optic evanescent wave sensor
| Autor: | Ruohua Wu, Nianbing Zhong, Qiang Liao, Xin Xin, Yanyan Cen, Zhengkun Wang |
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| Rok vydání: | 2016 |
| Předmět: |
Optical fiber
Materials science Polymers Biomedical Engineering Biophysics 02 engineering and technology Biosensing Techniques engineering.material 01 natural sciences law.invention 010309 optics Background noise Mice Optics law 0103 physical sciences Electrochemistry Animals Fiber Optic Technology Surface layer Optical Fibers Balsams business.industry Germanium Goats Doping General Medicine Equipment Design 021001 nanoscience & nanotechnology Antibodies Anti-Idiotypic Drug Combinations Canada balsam Immunoglobulin G engineering Gutta-Percha Zinc Oxide 0210 nano-technology business Layer (electronics) Refractive index Sensitivity (electronics) Biotechnology |
| Zdroj: | Biosensorsbioelectronics. 91 |
| ISSN: | 1873-4235 |
| Popis: | We present a novel four-layer structure consisting of bottom, second, third, and surface layers in the sensing region, for a D-shaped step-index fiber-optic evanescent wave (FOEW) sensor. To reduce the background noise, the surface of the longitudinal section in the D-shaped region is coated with a light-absorbing film. We check the morphologies of the second and surface layers, examine the refractive indices (RIs) of the third and surface layers, and analyze the composition of the surface layer. We also investigate the effects of the thicknesses and RIs of the third and surface layers and the LA film on the light transmission and sensitivity of the FOEW sensors. The results highlight the very good sensitivity of the proposed FOEW sensor with a four-layer structure, which reached −0.077 (μg/l)−1 in the detection of the target antibody; the sensitivity of the novel FOEW sensor was 7.60 and 1.52 times better than that of a conventional sensor with a core–cladding structure and an FOEW sensor with a three-layer structure doped with GeO2. The applications of this high-sensitivity FOEW sensor can be extended to biodefense, disease diagnosis, and biomedical and biochemical analysis. |
| Databáze: | OpenAIRE |
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