Clinical features of ceroid lipofuscinosis in border collie dogs
| Autor: | V. P. Studdert, R W Mitten |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Male
Litter (animal) Pediatrics medicine.medical_specialty Pathology Breeding Motor Activity Blindness Dogs Neuronal Ceroid-Lipofuscinoses medicine Ceroid lipofuscinosis Animals Dog Diseases Motor activity General Veterinary business.industry Mean age General Medicine medicine.disease Pedigree Aggression Border Collie Female business |
| Zdroj: | Australian Veterinary Journal. 68:137-140 |
| ISSN: | 1751-0813 0005-0423 |
| DOI: | 10.1111/j.1751-0813.1991.tb03156.x |
| Popis: | Ceroid lipofuscinosis was diagnosed by histopathological and histochemical findings in 17 related border collie dogs and by clinical signs in 6 of their litter mates. Behavioural changes, first hyperactivity and later aggression, commenced at 16 to 23 (mean 19.5) months of age. Motor abnormalities and blindness were observed at the mean ages of 20.8 and 21.2 months, respectively. All dogs were euthanased 1 to 6 months after the onset of clinical signs, mean age 23.1 months. Pedigree data supported an autosomal recessive mode of inheritance. |
| Databáze: | OpenAIRE |
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