Prevalence and risk factors for methicillin-resistant Staphylococcus aureus in an HIV-positive cohort
| Autor: | Jason E. Farley, Karen C. Carroll, Tracy L. Ross, Paul Sacamano, Matthew J. Hayat |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
Male Risk medicine.medical_specialty Epidemiology HIV Infections Nose medicine.disease_cause Article Specimen Handling Cohort Studies Acquired immunodeficiency syndrome (AIDS) Risk Factors Interquartile range Antiretroviral Therapy Highly Active Surveys and Questionnaires Internal medicine Prevalence medicine Humans Generalized estimating equation business.industry Health Policy Public Health Environmental and Occupational Health HIV Odds ratio Staphylococcal Infections Viral Load Anatomic site medicine.disease Methicillin-resistant Staphylococcus aureus CD4 Lymphocyte Count Hospitalization Cross-Sectional Studies Infectious Diseases Anti-Retroviral Agents Socioeconomic Factors Specimen collection Baltimore Cohort Immunology Female business Viral load |
| Zdroj: | American Journal of Infection Control. 43:329-335 |
| ISSN: | 0196-6553 |
| Popis: | BackgroundPersons living with HIV (PLWH) are disproportionately burdened with methicillin-resistant Staphylococcus aureus (MRSA). Our objective was to evaluate prevalence and risks for MRSA colonization in PLWH.MethodsAdults were recruited from Johns Hopkins University AIDS Service in Baltimore, Maryland. A risk questionnaire and specimen collection from anatomic sites with culture susceptibility and genotyping were completed. Generalized estimating equation modeling identified MRSA colonization risk factors.ResultsOf 500 participants, most were black (69%), on antiretroviral therapy (ART) (87%), with undetectable viral loads (73.4%). Median CD4 count was 487 cells/mm3 (interquartile range, 316-676.5 cells/mm3). MRSA prevalence was 15.4%, predominantly from the nares (59.7%). Forty percent were nares negative but were colonized elsewhere. Lower odds for colonization were associated with recent sexual activity (adjusted odds ratio [AOR] = 0.84, P $75,000; AOR = 2.68, P |
| Databáze: | OpenAIRE |
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