Towards smart biomanufacturing: a perspective on recent developments in industrial measurement and monitoring technologies for bio-based production processes

Autor:	Isuru A. Udugama, Rasmus Fjordbak Nielsen, Katrin Pontius, Christoph Bayer, Krist V. Gernaey, Helena Junicke, Seyed Soheil Mansouri, Pau Cabañeros Lopez, Carina L. Gargalo, Aliyeh Hasanzadeh
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	0106 biological sciences Engineering Technology Biotechnology Methods - Original Paper Big data Bioengineering 01 natural sciences Applied Microbiology and Biotechnology 03 medical and health sciences Automation 010608 biotechnology Control Smart biomanufacturing Production (economics) Industry Biomanufacturing Productivity 030304 developmental biology 0303 health sciences Harmony (color) business.industry Sensors Industry 4.0 Engineering management Upgrade Work (electrical) business Bioprocesses Biotechnology
Zdroj:	Journal of Industrial Microbiology & Biotechnology Gargalo, C L, Udugama, I, Pontius, K, Lopez, P C, Nielsen, R F, Hasanzadeh, A, Mansouri, S S, Bayer, C, Junicke, H & Gernaey, K V 2020, ' Towards smart biomanufacturing: a perspective on recent developments in industrial measurement and monitoring technologies for bio-based production processes ', Journal of Industrial Microbiology and Biotechnology, vol. 47, pp. 947–964 . https://doi.org/10.1007/s10295-020-02308-1
ISSN:	1476-5535 1367-5435
DOI:	10.1007/s10295-020-02308-1
Popis:	The biomanufacturing industry has now the opportunity to upgrade its production processes to be in harmony with the latest industrial revolution. Technology creates capabilities that enable smart manufacturing while still complying with unfolding regulations. However, many biomanufacturing companies, especially in the biopharma sector, still have a long way to go to fully benefit from smart manufacturing as they first need to transition their current operations to an information-driven future. One of the most significant obstacles towards the implementation of smart biomanufacturing is the collection of large sets of relevant data. Therefore, in this work, we both summarize the advances that have been made to date with regards to the monitoring and control of bioprocesses, and highlight some of the key technologies that have the potential to contribute to gathering big data. Empowering the current biomanufacturing industry to transition to Industry 4.0 operations allows for improved productivity through information-driven automation, not only by developing infrastructure, but also by introducing more advanced monitoring and control strategies.
Databáze:	OpenAIRE
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