A Working Hypothesis on Vesicular Lesions Related to COVID-19 Infection, Koebner Phenomena Type V, and a Short Review of Related Data
| Autor: | Lucretia Anghel, Silvia Fotea, Alin Laurentiu Tatu, Eduard Drima Polea, Lawrence Chukwudi Nwabudike, Liliana Baroiu, Valentin Chioncel, Thomas Nadasdy |
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| Rok vydání: | 2021 |
| Předmět: |
Coronavirus disease 2019 (COVID-19)
viruses Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Koebner phenomenon Inflammation Dermatology Working hypothesis medicine.disease_cause Virus Proinflammatory cytokine 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine medicine wolf isotopic response SARS-CoV-2 business.industry vesicular rash Varicella zoster virus COVID-19 virus diseases Hypothesis Clinical Cosmetic and Investigational Dermatology 030220 oncology & carcinogenesis locus minoris resistentiae Immunology medicine.symptom business |
| Zdroj: | Clinical, Cosmetic and Investigational Dermatology |
| ISSN: | 1178-7015 7516-0900 |
| DOI: | 10.2147/ccid.s307846 |
| Popis: | Alin Laurentiu Tatu,1,2,* Liliana Baroiu,3,4,* Silvia Fotea,4,5,* Lucretia Anghel,6,7 Eduard Drima Polea,6,8,* Thomas Nadasdy,1 Valentin Chioncel,9,* Lawrence Chukwudi Nwabudike10 1Dermatology Department, “St. Parascheva” Clinical Hospital of Infectious Diseases, Galati, Romania; 2Faculty of Medicine and Pharmacy, Clinical Medical Department, Dermatology, Medical and Pharmaceutical Research Unit, Competitive, Interdisciplinary Research Integrated Platform, ReForm-UDJG “DunÄrea de Jos” University, Galati, Romania; 3Infectious Diseases Department, “St. Parascheva” Clinical Hospital of Infectious Diseases, Galati, Romania; 4Faculty of Medicine and Pharmacy, Clinical Medical Department, “DunÄrea de Jos” University, Galati, 800010, Romania; 5Sf Ioan Clinical Hospital of Pediatrics, Galati, Romania; 6Department of Clinical Medicine, Faculty of Medicine and Pharmacy, “DunÄrea de Jos” University, GalaÈi, 800010, Romania; 7Internal Medicine Department, Sf Andrei Clinical Emergency Hospital, Galati, Romania; 8Elisabeta Doamna Clinical Hospital of Psychiatry, Galati, Romania; 9Department of Cardio-Thoracic Pathology, Faculty of Medicine, ‘Carol Davila’ University of Medicine and Phamacy, Bucharest, 050474, Romania; 10N. Paulescu National Institute of Diabetes, Bucharest, Romania*These authors contributed equally to this workCorrespondence: Thomas NadasdySpitalul Clinic de Boli Infectioase “Sf. Cuvioasa Parascheva”, Str. Traian, Nr. 393, Galati, 800179, RomaniaTel +40 751609000Email thomas.nadasdy@gmail.comLucretia AnghelFacultatea de MedicinÄ Èi Farmacie,Str. Al. I. Cuza Nr. 35, Galati, 800216, RomaniaTel +40 740050224Email anghel_lucretia@yahoo.comAbstract: SARS-CoV-2 has recently been associated with the reactivation of varicella zoster virus in patients. This is potentially an observation of a local susceptibility of the skin in areas of vesicle formation. This article explores the dermatologic manifestations that have been linked to the SARS-CoV-2 virus, their infectious risk, as well as potential confounding factors. An isotopic response may be occurring due to the occurrence of an immunocompromised district incited by sustained inflammation mediated by inflammatory cytokines.Keywords: COVID-19, SARS-CoV-2, Koebner phenomenon, wolf isotopic response, locus minoris resistentiae, vesicular rash |
| Databáze: | OpenAIRE |
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