Changes of Carbohydrate-Deficient Transferrin in Chronic Alcoholism
| Autor: | H. Niederhofer, H. Fritzsche, H. Steurer, P. König, R. Haller, R. Wölfle, P. Weiss |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
Adult
Male medicine.medical_specialty Temperance media_common.quotation_subject Carbohydrate deficient transferrin Biology Liver Function Tests Internal medicine Chronic alcoholism Liver enzyme medicine Humans Biological Psychiatry media_common chemistry.chemical_classification Sex Characteristics medicine.diagnostic_test Transferrin Middle Aged Abstinence Alcoholism Psychiatry and Mental health Neuropsychology and Physiological Psychology Endocrinology Liver chemistry Female Liver function tests Biomarkers Sex characteristics |
| Zdroj: | Neuropsychobiology. 32:192-196 |
| ISSN: | 1423-0224 0302-282X |
| DOI: | 10.1159/000119235 |
| Popis: | Compared with other well established liver enzyme parameters, carbohydrate-deficient transferrin (CDT) offers a new method for the identification of chronic alcoholism. The dependence of CDT and alcoholism/abstinence was studied in 29 controls and 64 alcoholics (both groups comprising men and women). In contrast to the currently used parameters GOT, GPT, gammaGT, LDH and MCV, CDT measures chronic alcoholism exclusively. CDT is dependent on sex but not age. In chronic alcoholism its rate increases significantly, but drops quickly after a short time of abstinence. CDT variations may be a specific and sensitive indicator of alcoholism or abstinence and possibly the duration. |
| Databáze: | OpenAIRE |
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