Ionic Liquids in Drug Delivery
| Autor: | Armando J. D. Silvestre, Mara G. Freire, Carmen S. R. Freire, Sónia N. Pedro |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
active pharmaceutical ingredients
formulations stimuli-responsive systems Science Ionic bonding 02 engineering and technology 010402 general chemistry 01 natural sciences Ion ionic liquids chemistry.chemical_compound chemistry.chemical_classification Active ingredient permeation enhancers Solvation Active pharmaceutical ingredients Formulations Polymer 021001 nanoscience & nanotechnology Ionic liquids 0104 chemical sciences chemistry Chemical engineering Drug delivery Ionic liquid drug delivery Stimuli-responsive systems Permeation enhancers 0210 nano-technology Volatility (chemistry) |
| Zdroj: | Encyclopedia, Vol 1, Iss 27, Pp 324-339 (2021) |
| ISSN: | 2673-8392 |
| Popis: | Ionic liquids (ILs) are molten salts composed of a large organic cation and an organic/inorganic anion. Due to their ionic character, most ILs present advantageous properties over conventional solvents, such as negligible volatility at atmospheric conditions and high thermal and chemical stabilities. The wide variety of IL anion–cation combinations allows these solvents to be designed to display a strong solvation ability for a myriad of active pharmaceutical ingredients (APIs) and (bio)polymers. Given these properties, ILs have been used as solvents and as formulation components in different areas of drug delivery, as well as novel liquid forms of APIs (API-ILs) applied in different stages of development of novel drug delivery systems. Furthermore, their combination with polymers and biopolymers has enabled the design of drug delivery systems for new therapeutic routes of administration. |
| Databáze: | OpenAIRE |
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